Biogemma (BGA)
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Location : Clermont-Ferrand / France |
| Leader : Sebastien PRAUD | |
| Website : www.biogemma.fr/indexuk.php |
Competences:
Biogemma is a biotech company owned by three major European field seed companies: Limagrain, Euralis and RAGT, and Sofiprotéol and Unigrains. Biogemma is specialized in field crops: maize, Wheat and Oil seed crops. Biogemma objectives are to provide its shareholders with new genetic variability by GMO traits and markers on gene of interest to better monitor existing genetic variability. Biogemma has been widely involved in a number of projects in collaboration with public/private partners, including GENOPLANTE and former EC projects. Biogemma has developed a large range of expertises in genetic engineering and in genomics. Large scale bioinformatics analysis (tool development and data analysis), QTL analysis, gene mapping, functional analysis (KO, genetic engineering), cloning, and Linkage disequilibrium analysis are among Biogemma standard methodologies. High-throughput technologies in the domains of DNA chips and BAC libraries have also been developed.
These know-how and skills are used in the framework of various undergoing projects, for instance, within Genoplante: WheatGrowth (GNP05072C) is the acronym of a project that investigates the influence of the vegetative and reproductive organ development on wheat yield achievement as well as genotype adaptation to environmental conditions. ProtNblé (GPLA06047C) focuses on the improvement of nitrogen use efficiency (NUE) of wheat cultivars (bread wheat and durum wheat) to optimise crop yield and quality while safeguarding the environment.
Role:
Biogemma will work together with its shareholder: Limagrain, which are the European leader in cereal breeding.
Staff members’ profile:
Dr. Sébastien Praud (Biogemma) is the leading scientist in wheat genomics within Alain Murigneux group. His main activities are dedicated to QTL fine mapping, Bioinformatics, SNP discovery and association mapping on various agronomic traits (disease resistance, Yield..).
References:
- Ravel C, Praud S, Murigneux A, Canaguier A, Sapet F, Samson D, Balfourier F, Dufour F, Chalhoub B, Brunel D, Béckert M and Charmet G (2006) Single-nucleotide polymorphism frequency in a set of selected lines of bread wheat (Triticum aestivum L.) Genome 49;1131-1139.
- Ravel C, Nagy I, Martre P, Sourdille P, Balfourier F, Giancolla S, Praud S and Charmet G (2006) Single nucleotide polymorphism, genetic mapping, and expression of genes coding for the DOF wheat prolamin-box binding factor. Functional Integr Genomics March 28.
- Ravel C, Praud S, Murigneux A, Linossier L, Dardevet M, Balfourier F, Dufour P, Brunel D and Charmet G (2006) dentification of Glu-B1-1 as a candidate gene for the quantity of high-molecular-weight glutenin in bread wheat (Triticum aestivum L.) by means of an association study. Theoretical and Applied Genetics 112(4):738-43.
- Crepieux S, Lebreton C, Flament P, Charmet G (2005). Application of a new IBD-based QTL mapping method to common wheat breeding population: analysis of kernel hardness and dough strength. Theor Appl Genet 111:1409:1419
- Crepieux S, Lebreton C, Servin B, Charmet G (2004) QTL detection in multi-cross inbred designs: recovering QTL-IBD status information from marker data. Genetics 168:1737-1749
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This project is supported by the European Commission under the 7th Framework Programme
for Research and Technological Development