University of Haifa (HU)
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Location : Haifa / Israel |
| Leader : Tzion FAHIMA | |
| Website : www.haifa.ac.il/index_eng.html |
Competences:
Haifa University is represented by two groups, experienced in cereal structural genomics (Fahima's group) and bioinformatics related to genome mapping (Korol's group). HU expertise include: genetic mapping of disease resistance genes derived from wild emmer wheat; QTL mapping of domestication related traits; using comparative genomic approaches for fine mapping of disease resistance genes; construction of tetraploid wheat BAC library; physical mapping and positional cloning of high grain protein content QTL (Gpc-B1) in wheat; development of a methodology and efficient algorithms for building dense molecular genetic maps and map verification; methods for consensus mapping; new methods for multiple-trait QTL analysis and fine QTL mapping; a new bioinformatics approach for contig assembly and physical mapping.
Role:
HU will participate in the following WPs: WP1 - FPC assembly of 1BS; WP2 - anchoring the short arm of 1BS using the contigs assembled in WP1; WP3 - positional cloning of the stripe rust resistance gene YrH52; WP5 - development of bioinformatic tools for contig assembly and ordering of BAC clones based on fingerprinting data; and WP6 – training course.
Staff member’s profile:
Prof. Abraham Korol is full professor for genetics at the University of Haifa. He was educated as computer scientist (BSc and MSc) and then as geneticist (PhD and Dr. of Science in Genetics from Moscow Institute of General Genetics of USSR Academy of Science and St-Petersburg University, respectively). He worked first at the Institute of Ecological Genetics at the Moldavian Academy of Science and then at later at the Institute of Evolution, University of Haifa. His main activities are related to mathematical genetics, populations’ genetics and evolution of recombination, plant genomics and evolution, genetics of quantitative traits, and bioinformatics. He served as a member of the steering committee of the scientific strategic resources of the Israeli Ministry of Science and as the Israeli representative in the barley working group of European Plant Genetic Resources.
Prof. Tzion Fahima is associate professor for plant genomics at the University of Haifa. He was educated as plant pathologist and molecular biologist at the Hebrew University of Jerusalem (BSc and PhD), Drexel University (postdoc), Texas A&M University (postdoc) and University of California (sabbatical). He established the laboratory of plant genomics and disease resistance at the Institute of Evolution, University of Haifa. He is a member of the management committee of the Israeli Gene Bank for Plant Genetic Resources. His main activities are related to exploiting the wild gene pool of the progenitors of cultivated cereals using genomic technologies; evolution of domestication; functional genomics of biotic and abiotic stress resistance.
Mrs. Tamar Krugman: is a research associate at the plant molecular evolution laboratory, the Institute of Evolution, University of Haifa. Her main activities are related to exploiting the wild gene pool of the progenitors of cultivated cereals using genomic technologies; evolution of domestication; genetic mapping; and functional genomics of abiotic stress resistance.
References:
- Suprunova T., Krugman T., Distelfeld A., Fahima T., Nevo E. and Korol A. 2007. Identification of a novel gene (Hsdr4) involved in water stress tolerance in wild barley. Plant Molecular Biology, online first: DOI 10.1007/s11103-006-9131-x.
- Uauy C., Distelfeld A., Fahima T., Blechl A., Dubcovsky J. 2006. A NAC gene regulating senescence improves grain protein, Zn, and Fe content in wheat. Science, 314: 1298-1301.
- Distelfeld A., Uauy C., Fahima T., Dubcovsky J. 2006. Physical map of the wheat high-grain protein content gene Gpc-B1 and development of a high-throughput molecular marker. New Phytologist, 169: 753-763.
- Uauy C., Brevis J.C., Chen X., Khan I., Jackson L., Chicaiza O., Distelfeld A., Fahima T. and Dubcovsky J. 2005. High-temperature adult plant (HTAP) stripe rust resistance gene Yr36 from Triticum turgidum ssp. dicoccoides is closely linked to the grain protein content locus Gpc-B1. TAG, 112: 97–105.
- Mester, D., Y. Ronin, M. Korostishevsky, V. Pikus, A. Glazman and A.B. Korol 2005. Multilocus consensus genetic maps (MCGM): Formulation, algorithms and results. Computat. Biol. & Chemistry, 30: 12–20.
- Yan, L., Loukoianov, A., Tranquilli, G., Helguera, M., Fahima, T. and Dubcovsky, J. 2003. Positional cloning of wheat vernalization gene VRN1. PNAS, 100: 6263-6268.
- Cenci, A., Chantret, N., Kong, X., Gu, Y., Anderson, O., Fahima, T., Distelfeld, A., Dubcovsky, J. 2003. Construction and characterization of a half million clones BAC library of durum wheat (Triticum turgidum ssp. durum). TAG, 107: 931-939.
- Mester D., Ronin Y., Minkov D., Nevo E., Korol A. 2003. Constructing large scale genetic maps using evolutionary strategy algorithm. Genetics, 165: 2269-2282.
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This project is supported by the European Commission under the 7th Framework Programme
for Research and Technological Development