Scottish Crop Research Institute (SCRI)
 |
Location : Dundee / UK |
| Leader : Robbie WAUGH | |
| Website : www.scri.ac.uk |
Competences:
The Scottish Crop Research Institute is a major international centre for research on the underlying biological processes common to all plant science and crop growth. It is the only plant-science based Institute in Scotland, and the range of complementary skills assembled at the institute represents one of its unique features. SCRI participates in the integrated program of research and development in agricultural, environmental and biological sciences supported by the Scottish Executive Environment and Rural Affairs Department (SEERAD). The PI’s have proven expertise in genetics, genomics and bioinformatics of crop plants, including barley, and have contributed to many of the key genomics and genetics enabling technologies that are deployed globally today.
Role:
SCRI will contribute to WP2 and indirectly to WP4. SCRI will i) develop a highly multiplex BAC anchoring platform based on a custom Agilent Microarray, ii) use this for BAC library screening in order to efficiently anchor barley physical and genetic maps, iii) assist in the development of 1H and 3H specific OPA's based on mapped barley genes and 1H & 3H rice orthologs, iv) optimise microarray anchoring for use on wheat BAC pools for comparative mapping and v) conduct intra- and inter- specific structural and functional analyses using the comparative physical maps.
Staff members’ profile:
Prof. Robbie Waugh is head of Genetics at SCRI and Dr. David Marshall is head of the SCRI bioinformatics group within Genetics. Each are engaged in a number of national and trans-national programs and both are acknowledged internationally in barley genetics and genomics. Together they have over 40 years research experience in plant genetics, genomics and bioinformatics and have published over 200 papers in international peer reviewed journals. Their closely aligned research aims are to exploit genomics and informatics technologies and resources to link derived genotypes to key phenotypic characters. Bio-diverse germplasm collections, state of the art genomics technologies and informatics tools and resources underpin their research program. They will be assisted by L. Cardle, A. Druka, P. Hedley and N. McCallum.
References:
- Bhat, P.R, Close, T.J., Condamine, P., Fenton, R.D., Graner, A., Madishetty, K., Mandal, J., Marshall, D., Ramsay, L., Roose, M.L., Rostoks, N., Stein, N., Svensson, J.T., Wanamaker, S. and Waugh, R. Development of high-throughput SNP genotyping platforms for plants with EST resources. Plant Journal (Submitted)
- Z. W. Luo, E. Potokina, A. Druka, R. Wise, R. Waugh, and M. J. Kearsey. SFP Genotyping From Affymetrix Arrays Is Robust But Largely Detects Cis-acting Expression Regulators. Genetics June 1, 2007 176:789-800
- Rostoks, N., Ramsay, L., MacKenzie, K., Cardle, L., Svensson, J.T., Bhat, P., Stein, N., Varshney, R.J., Marshall, D., Graner, A., Close, T.J. & Waugh, R. (2006) Human-induced population structure in inbreeding crop species facilitates whole genome association mapping. Proceedings of the National Academy of Sciences, USA 103: 18656-18661
- Waugh, R., Leader, D.J., McCallum, N. & Caldwell, D. (2006) Harnessing the potential of induced biological diversity. Trends in Plant Science 11: 71-79
- Druka, A., Muehlbauer, G., Druka, I., Caldo, R., Baumann, U., Rostoks, N., Schreiber, A., Wise, R., Close, T., Kleinhofs, A., Graner, A,, Schulman, A., Langridge, P., Sato, K., Hayes, P., McNicol, J., Marshall, D. & Waugh, R. (2006) An atlas of gene expression from seed to seed during barley development. Funct Integr Genomics 6: 202-211
- Rostoks, N., Mudie, S., Cardle, L., Russell, J.R., Ramsay, L., Booth, A., Svensson, J.T., Wanamaker, S., Walia, H., Rodriguez, E.M., Hedley, P.E., Liu, H., Morris, J., Close, T.J., Marshall, D.F. & Waugh, R. (2005) SNP-based barley integrated linkage map developed from genes responsive to abiotic stress identifies regions of conserved synteny in barley and rice. Molecular Genetics and Genomics 274; 515-524.
- Rostoks, N., Borevitz, J.O., Hedley, P.E., Russell, J.R., Mudie, S., Morris, J., Cardle, L., Marshall, D.F. & Waugh, R. (2005) Single feature polymorphism discovery in the barley transcriptome. Genome Biology 6 (6): art. no. R54 2005.
- Piffanelli, P., Ramsay, L., Waugh, R., Benabdelmouna, A., D'Hont, A., Hollricher, K., Jorgensen, J.H., Lefert, P.S. & Panstruga, R. (2004) A barley cultivation-associated polymorphism conveys resistance to powdery mildew. Nature 430, 887-891.
- Caldwell, D., McCallum, N., Shaw, P., Muehlbauer, G.J. & Waugh, R. (2004) A structured mutant population for forward and reverse genetics in barley (Hordeium vulgare L.). Plant Journal 40, 143-150
- Thangavelu, M., James, A., Bankier, A., Bryan, G.J., Dear, P. & Waugh, R. 2003. HAPPY mapping in a plant genome: reconstruction and analysis of a high-resolution physical map of a 1.9 Mbp region of Arabidopsis thaliana Chromosome 4. Plant Biotechnology Journal 1, 23-33
Show all the institutions
This project is supported by the European Commission under the 7th Framework Programme
for Research and Technological Development